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Correction to: Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis

The original article was published in Cell Communication and Signaling 2019 17:23

Correction to: Zhang et al. Cell Communication and Signaling (2019) 17:23

https://doi.org/10.1186/s12964-019-0332-8

Following publication of the original article [1], the authors reported an error in Fig. 3. The corrected Fig. 3 is given below. Please note that these revisions do not affect the overall conclusions reported in the article. The authors apologise for the error and any inconvenience caused.

Fig. 3
figure1

The changes in metabolic enzymes contribute to the low levels of pyruvate. a Cells were treated with 1 μM ML265 for 24 h and subjected to western blot. b PKM2 overexpressed cells and their counterparts were subjected to western blot. c The oxygen consumption rates (OCR) of PKM2-overexpressed cells and control cells were detected at different time points. OCR under oligomycin, carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone (FCCP), and antimycin A/rotenone treatments, respectively. d Cells were treated with 10 μM Gossypol-Acetic Acid (GAA) for 24 h and subjected to western blot. e LDHA knockdown cells and their counterparts were subjected to western blot. f The OCR of LDHA knockdown cells and control cells were detected at different time points. g Cells were treated with 1 μM ML265 and 10 μM GAA for 24 h, then subjected to western blot. h Cells were treated with 1 μM ML265 and 10 μM GAA for 24 h, the concentrations of the metabolites in GC cells were measured by Mass spectrometry (MS) and normalized to their protein level. i The OCR of cells were detected at different time points after they treated with 1 μM ML265 and 10 μM GAA for 24 h. Data represent the Mean ± SEM, n ≥ 3. *p < 0.05, **p < 0.01, NS not significant

Reference

  1. 1.

    Zhang, et al. Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis. Cell Commun Signal. 2019;17:23 https://doi.org/10.1186/s12964-019-0332-8.

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Correspondence to Jian-lin Wu or Lei Wang or Xiaoping Zou.

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