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  1. Coinfection with HIV and Plasmodium parasites is fairly common, but the sequence of infection with these two pathogens and their impact on disease progression are poorly understood.

    Authors: Guangjie Liu, Li Qin, Youjia Li, Siting Zhao, Mikhail Shugay, Yongxiang Yan, Yijian Ye, Yue Chen, Cuizhu Huang, Nashun Bayaer, Dickson Adah, Hui Zhang, Zhong Su and Xiaoping Chen
    Citation: Cell Communication and Signaling 2022 20:101
    Content type: Research Published on:

  2. NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription factor that defends against endogenous or exogenous stressors. By inducing several cytoprotective and detoxifying gene expre...

    Authors: Farhad Pouremamali, Amir Pouremamali, Mehdi Dadashpour, Narges Soozangar and Farhad Jeddi
    Citation: Cell Communication and Signaling 2022 20:100
    Content type: Review Published on:

  3. Bone morphogenetic proteins (BMP) are evolutionarily conserved morphogens that are reactivated in lung carcinomas. In lung cancer cells, BMP signaling suppresses AMP activated kinase (AMPK) by inhibiting LKB1....

    Authors: Arindam Mondal, Jacques Roberge, John Gilleran, Youyi Peng, Dongxuan Jia, Moumen Akel, Yash Patel, Harrison Zoltowski, Anupama Doraiswamy and John Langenfeld
    Citation: Cell Communication and Signaling 2022 20:99
    Content type: Research Published on:

  4. Aspergillus fumigatus infection is difficult to diagnose clinically and can develop into invasive pulmonary aspergillosis, which has a high fatality rate. The incidence of Aspergillus fumigatus infection has incr...

    Authors: Dong-Ming Wu, Miao He, Yang-Yang Zhao, Shi-Hua Deng, Teng Liu, Ting Zhang, Feng Zhang, Yuan-Yi Wang and Ying Xu
    Citation: Cell Communication and Signaling 2022 20:98
    Content type: Research Published on:

  5. Cancer progression involves several biological steps where angiogenesis is a key tumorigenic phenomenon. Extracellular vesicles (EVs) derived from tumor cells and other cells in the tumor microenvironment (TME...

    Authors: Jian Gao, Xiaodong Zhang, Lei Jiang, Yan Li and Qianqian Zheng
    Citation: Cell Communication and Signaling 2022 20:97
    Content type: Review Published on:

  6. Viruses must adapt to the environment of their host cells to establish infection and persist. Diverse mammalian cells, including virus-infected cells, release extracellular vesicles such as exosomes containing...

    Authors: Yoshitaka Sato, Masahiro Yaguchi, Yusuke Okuno, Hanako Ishimaru, Ken Sagou, Somi Ozaki, Takeshi Suzuki, Tomoki Inagaki, Miki Umeda, Takahiro Watanabe, Masahiro Fujimuro, Takayuki Murata and Hiroshi Kimura
    Citation: Cell Communication and Signaling 2022 20:95
    Content type: Research Published on:

  7. Chemoattractant is critical to recruitment of osteoclast precursors and stimulates tumor bone metastasis. However, the role of chemoattractant in bone metastasis of colorectal cancer (CRC) is still unclear.

    Authors: He Yang, Li Jian, Qian Jin, Kang Xia, Wang Cai-ru, Sheng Jun, Huang Chen, Wang Wei, Song Ben-jing, Li Shi-hong, Long Shi-wei, Wu Juan and Zheng Wei
    Citation: Cell Communication and Signaling 2022 20:94
    Content type: Research Published on:

  8. Targeting AKT suppresses tumor growth through inducing apoptosis, however, during which whether other forms of cell death occurring is poorly understood.

    Authors: Yizheng Zhang, Chuchu Zhang, Jiehan Li, Meimei Jiang, Shuning Guo, Ge Yang, Lingling Zhang, Feng Wang, Shiqi Yi, Jiangang Wang, Yang Fu and Yingjie Zhang
    Citation: Cell Communication and Signaling 2022 20:93
    Content type: Research Published on:

  9. Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer with poor prognosis and limited treatment. As a major component of the tumor microenvironment, tumor-associated macrophages ...

    Authors: Xiangzhou Chen, Mingqiang Yang, Jiang Yin, Pan Li, Shanshan Zeng, Guopei Zheng, Zhimin He, Hao Liu, Qian Wang, Fan Zhang and Danyang Chen
    Citation: Cell Communication and Signaling 2022 20:92
    Content type: Research Published on:

  10. Authors: Rebar N. Mohammed, Mohsen Khosravi, Heshu Sulaiman Rahman, Ali Adili, Navid Kamali, Pavel Petrovich Soloshenkov, Lakshmi Thangavelu, Hossein Saeedi, Navid Shomali, Rozita Tamjidifar, Alireza Isazadeh, Ramin Aslaminabad and Morteza Akbari
    Citation: Cell Communication and Signaling 2022 20:91
    Content type: Correction Published on:

    The original article was published in Cell Communication and Signaling 2022 20:81

  11. Authors: Rebar N. Mohammed, Rozita Tamjidifar, Heshu Sulaiman Rahman, Ali Adili, Shadi Ghoreishizadeh, Hossein Saeedi, Lakshmi Thangavelu, Navid Shomali, Ramin Aslaminabad, Faroogh Marofi, Mina Tahavvori, Svetlana Danishna, Morteza Akbari and Gülinnaz Ercan
    Citation: Cell Communication and Signaling 2022 20:90
    Content type: Correction Published on:

    The original article was published in Cell Communication and Signaling 2022 20:79

  12. Growth differentiation factor-11 (GDF-11), also known as bone morphogenetic protein-11, belongs to the transforming growth factor-beta superfamily. GDF-11 was first identified as an important regulator during ...

    Authors: Ze Wu, Lanlan Fang, Sizhu Yang, Yibo Gao, Zhen Wang, Qingxue Meng, Xuan Dang, Ying-Pu Sun and Jung-Chien Cheng
    Citation: Cell Communication and Signaling 2022 20:89
    Content type: Research Published on:

  13. The existence of mesenchymal stem cells (MSCs) in Schneiderian membrane has not been determined. The aim of this study is to investigate whether there are MSCs in Schneiderian membrane, and the effect of plate...

    Authors: Jia Wang, Yue Sun, Yiping Liu, Jize Yu, Xiaolin Sun, Lin Wang and Yanmin Zhou
    Citation: Cell Communication and Signaling 2022 20:88
    Content type: Research Published on:

  14. Esophageal Squamous Cell Carcinoma (ESCC) was characterized as a regional-prevalent and aggressive tumor with high morbidity and mortality. NIMA-related kinase 2 (NEK2) is an interesting oncogene, the alterati...

    Authors: Wei Su, Hao Hu, Qiurong Ding, Min Wang, Yan Zhu, Zhaochao Zhang, Zihan Geng, Shengli Lin and Pinghong Zhou
    Citation: Cell Communication and Signaling 2022 20:87
    Content type: Research Published on:

  15. TGF-β1 promotes keratinocyte migration and re-epithelialization of cutaneous wounds during the wound healing process. Decreased SOCS7 expression has been associated with increased healing potential. However, t...

    Authors: Xiao Feng, Wei Feng, Yu Ji, Tingting Jin, Jingyu Li and Jincai Guo
    Citation: Cell Communication and Signaling 2022 20:86
    Content type: Research Published on:

  17. Neonatal hypoxic-ischemic brain injury (HIE) is caused by perinatal asphyxia, which is associated with various confounding factors. Although studies on the pathogenesis and treatment of HIE have matured, sub-h...

    Authors: Yihui Zheng, Luyao Li, Binwen Chen, Yu Fang, Wei Lin, Tianlei Zhang, Xiaoli Feng, Xiaoyue Tao, Yiqing Wu, Xiaoqin Fu and Zhenlang Lin
    Citation: Cell Communication and Signaling 2022 20:84
    Content type: Research Published on:

  18. Autoimmune hepatitis (AIH) is a chronic, immune-mediated liver dysfunction. The gut microbiota and T follicular helper (Tfh) cells play critical roles in the immunopathogenesis and progression of AIH. We aimed...

    Authors: Liang Ma, Liwen Zhang, Yun Zhuang, Yanbo Ding and Jianping Chen
    Citation: Cell Communication and Signaling 2022 20:83
    Content type: Research Published on:

  20. Balanced cell death and survival are among the most important cell development and homeostasis pathways that can play a critical role in the onset or progress of malignancy steps. Anastasis is a natural cell r...

    Authors: Rebar N. Mohammed, Mohsen Khosravi, Heshu Sulaiman Rahman, Ali Adili, Navid Kamali, Pavel Petrovich Soloshenkov, Lakshmi Thangavelu, Hossein Saeedi, Navid Shomali, Rozita Tamjidifar, Alireza Isazadeh, Ramin Aslaminabad and Morteza Akbari
    Citation: Cell Communication and Signaling 2022 20:81
    Content type: Review Published on:

    The Correction to this article has been published in Cell Communication and Signaling 2022 20:91

  21. A major goal in the discovery of cellular signaling networks is to identify regulated phosphorylation sites (“phosphosites”) and map them to the responsible protein kinases. The V2 vasopressin receptor is a G-...

    Authors: Kirby T. Leo, Chung-Lin Chou, Chin-Rang Yang, Euijung Park, Viswanathan Raghuram and Mark A. Knepper
    Citation: Cell Communication and Signaling 2022 20:80
    Content type: Research Published on:

  22. Coronavirus disease (COVID-19) is a viral infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The infection was reported in Wuhan, China, in late December 2019 ...

    Authors: Rebar N. Mohammed, Rozita Tamjidifar, Heshu Sulaiman Rahman, Ali Adili, Shadi Ghoreishizadeh, Hossein Saeedi, Lakshmi Thangavelu, Navid Shomali, Ramin Aslaminabad, Faroogh Marofi, Mina Tahavvori, Svetlana Danishna, Morteza Akbari and Gülinnaz Ercan
    Citation: Cell Communication and Signaling 2022 20:79
    Content type: Review Published on:

    The Correction to this article has been published in Cell Communication and Signaling 2022 20:90

  23. Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase family. Originally, it was identified as a membrane protein involved in maintaining plasma membrane asymmetry. However, studies ...

    Authors: Jessica Dal Col, Marìa Julia Lamberti, Annunziata Nigro, Vincenzo Casolaro, Elisabetta Fratta, Agostino Steffan and Barbara Montico
    Citation: Cell Communication and Signaling 2022 20:78
    Content type: Review Published on:

  25. Acute kidney injury (AKI) is associated with a severe decline in kidney function caused by abnormalities within the podocytes' glomerular matrix. Recently, AKI has been linked to alterations in glycolysis and ...

    Authors: Mohammed Alquraishi, Samah Chahed, Dina Alani, Dexter L. Puckett, Presley D. Dowker, Katelin Hubbard, Yi Zhao, Ji Yeon Kim, Laurentia Nodit, Huma Fatima, Dallas Donohoe, Brynn Voy, Winyoo Chowanadisai and Ahmed Bettaieb
    Citation: Cell Communication and Signaling 2022 20:76
    Content type: Research Published on:

  26. The transforming growth factor-beta (TGF-β) signaling pathway is an important pathway associated with the pathogenesis of osteoarthritis (OA). This study was to investigate the involvement of circRNAs in the T...

    Authors: Shiyuan Lin, Huizi Li, Biao Wu, Jie Shang, Ning Jiang, Rong Peng, Baizhou Xing, Xianghe Xu and Huading Lu
    Citation: Cell Communication and Signaling 2022 20:75
    Content type: Research Published on:

  27. Depression is one of the most common psychiatric diseases. The monoamine transmitter theory suggests that neurotransmitters are involved in the mechanism of depression; however, the regulation on serotonin pro...

    Authors: Bin Wang, Haixia Shi, Liyan Ren, Zhigang Miao, Bo Wan, Hao Yang, Xiaotang Fan, Jan-Ake Gustafsson, Miao Sun and Xingshun Xu
    Citation: Cell Communication and Signaling 2022 20:74
    Content type: Research Published on:

  28. Transcription factor c-Myc plays a critical role in various physiological and pathological events. c-Myc gene rearrangement is closely associated with multiple myeloma (MM) progression and drug resistance. The...

    Authors: Ruosi Yao, Menghui Zhang, Jian Zhou, Linlin Liu, Yan Zhang, Jian Gao and Kailin Xu
    Citation: Cell Communication and Signaling 2022 20:73
    Content type: Research Published on:

  29. The LH surge is a pivotal event that triggers multiple key ovarian processes including oocyte maturation, cumulus expansion, follicular wall rupture and luteinization of mural granulosa and theca cells. Recent...

    Authors: Philippe Godin, Mayra F. Tsoi, Martin Morin, Nicolas Gévry and Derek Boerboom
    Citation: Cell Communication and Signaling 2022 20:72
    Content type: Research Published on:

  30. Cholecystectomy (XGB) is widely recognized as a risk factor for colon cancer (CC). Continuous exposure of the colonic epithelium to deoxycholic acid (DCA) post-XGB may exert cytotoxic effects and be involved i...

    Authors: Yuxia Yao, Xiangji Li, Baohong Xu, Li Luo, Qingdong Guo, Xingyu Wang, Lan Sun, Zheng Zhang and Peng Li
    Citation: Cell Communication and Signaling 2022 20:71
    Content type: Research Published on:

    The Correction to this article has been published in Cell Communication and Signaling 2022 20:85

  31. Osteoarthritis (OA) is one of the main causes of disabilities among older people. To date, multiple disease-related molecular networks in OA have been identified, including abnormal mechanical loadings and loc...

    Authors: Ze Du, Xuanhe You, Diwei Wu, Shishu Huang and Zongke Zhou
    Citation: Cell Communication and Signaling 2022 20:70
    Content type: Review Published on:

  32. Many eukaryote cells produce membrane-enclosed extracellular vesicles (EVs) to establish cell-to-cell communication. Plant-derived EVs (P-EVs) contain proteins, RNAs, lipids, and other metabolites that can be ...

    Authors: Mohadeseh Nemati, Bipin Singh, Rakeeb Ahmad Mir, Mahdieh Nemati, Azadeh Babaei, Mahdi Ahmadi, Yousef Rasmi, Afsaneh Gholinejad Golezani and Jafar Rezaie
    Citation: Cell Communication and Signaling 2022 20:69
    Content type: Review Published on:

  33. As a new kind of non-coding RNAs (ncRNAs), tRNA derivatives play an important role in gastric carcinoma (GC). Nevertheless, the underlying mechanism tRNA derivatives were involved in was rarely illustrated.

    Authors: Weiguo Xu, Junyu Zheng, Xiao Wang, Bin Zhou, Huanqiu Chen, Gang Li and Feng Yan
    Citation: Cell Communication and Signaling 2022 20:68
    Content type: Research Published on:

  34. The Notch signaling pathway is a crucial regulator of cell differentiation as well as tissue organization, whose deregulation is linked to the pathogenesis of different diseases. NOTCH1 plays a key role in bre...

    Authors: Joanna Kałafut, Jakub Czapiński, Alicja Przybyszewska-Podstawka, Arkadiusz Czerwonka, Adrian Odrzywolski, Cecilia Sahlgren and Adolfo Rivero-Müller
    Citation: Cell Communication and Signaling 2022 20:67
    Content type: Methodology Published on:

  35. Notch signalling pathway plays a key role in metazoan biology by contributing to resolution of binary decisions in the life cycle of cells during development. Outcomes such as proliferation/differentiation dic...

    Authors: Filip Vujovic, Neil Hunter and Ramin M. Farahani
    Citation: Cell Communication and Signaling 2022 20:66
    Content type: Research Published on:

  36. Ezrin/radixin/moesin (ERM) proteins are members of the protein 4.1 superfamily and function as linkers that connect the actin cytoskeleton to the plasma membrane of cells. ERM also play critical role in the Li...

    Authors: Ning Ding, Pibao Li, Huiqing Li, Yunlong Lei and Zengzhen Zhang
    Citation: Cell Communication and Signaling 2022 20:65
    Content type: Research Published on:

  37. Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of the gastrointestinal tract. Accumulating evidence shows that the development of IBD is always accompanied by the dysbiosi...

    Authors: Zhilin Zhang, Huan Zhang, Tian Chen, Lin Shi, Daorong Wang and Dong Tang
    Citation: Cell Communication and Signaling 2022 20:64
    Content type: Review Published on:

  38. The tumor microenvironment consists of stromal cells, extracellular matrix, and physicochemical properties (e.g., oxygenation, acidification). An important element of the tumor niche are cancer-associated fibr...

    Authors: Justyna Mazurkiewicz, Aleksandra Simiczyjew, Ewelina Dratkiewicz, Katarzyna Pietraszek-Gremplewicz, Michał Majkowski, Magdalena Kot, Marcin Ziętek, Rafał Matkowski and Dorota Nowak
    Citation: Cell Communication and Signaling 2022 20:63
    Content type: Research Published on:

  39. Recent studies have indicated that some members of the tripartite motif (TRIM) proteins function as important regulators for non-small cell lung cancer (NSCLC), However, the regulatory mechanism underpinning a...

    Authors: Manman Liang, Lijing Wang, Zhengui Sun, Xingwu Chen, Hanli Wang, Lilong Qin, Wenying Zhao and Biao Geng
    Citation: Cell Communication and Signaling 2022 20:62
    Content type: Research Published on:

  40. Polycystic ovary syndrome (PCOS) is characterized by follicular dysplasia. An insufficient glycolysis-derived energy supply of granulosa cells (GCs) is an important cause of follicular dysplasia in PCOS. Folli...

    Authors: Jianping Cao, Peng Huo, Kuiqing Cui, Huimei Wei, Junna Cao, Jinyuan Wang, Qingyou Liu, Xiaocan Lei and Shun Zhang
    Citation: Cell Communication and Signaling 2022 20:61
    Content type: Research Published on:

  41. Apolipoprotein A-I binding protein (AIBP), a secreted protein, has been shown to play a pivotal role in the development of atherosclerosis. The function of intracellular AIBP, however, is not yet well characte...

    Authors: Meng Duan, Hainan Chen, Linjie Yin, Xiao Zhu, Petr Novák, Yuncheng Lv, Guojun Zhao and Kai Yin
    Citation: Cell Communication and Signaling 2022 20:60
    Content type: Research Published on:

  42. Apoptosis signal-regulating kinase 1-interacting protein 1 (AIP1) participates in inflammatory neovascularization induction. NADPH oxidase 4 (NOX4) produces reactive oxygen species (ROS), leading to an imbalan...

    Authors: Qingyu Li, Xia Hua, Liangpin Li, Xueyan Zhou, Ye Tian, Yang Deng, Min Zhang, Xiaoyong Yuan and Wei Chi
    Citation: Cell Communication and Signaling 2022 20:59
    Content type: Research Published on:

  43. The contribution of native or modified oligodendroglia-derived extracellular vesicles (OL-EVs) in controlling chronic inflammation is poorly understood. In activated microglia, OL-EVs contribute to the removal...

    Authors: Bram Van den Broek, Charlotte Wuyts, Angela Sisto, Isabel Pintelon, Jean-Pierre Timmermans, Veerle Somers, Vincent Timmerman, Niels Hellings and Joy Irobi
    Citation: Cell Communication and Signaling 2022 20:58
    Content type: Research Published on:

  44. The epithelial-mesenchymal transition (EMT) is a vital driver of tumor progression. It is a well-known and complex trans-differentiation process in which epithelial cells undergo morphogenetic changes with los...

    Authors: Fanyun Kong, Lihong Ma, Xing Wang, Hongjuan You, Kuiyang Zheng and Renxian Tang
    Citation: Cell Communication and Signaling 2022 20:57
    Content type: Review Published on:

  45. Microglia-mediated neuroinflammatory response following traumatic brain injury (TBI) is considered as a vital secondary injury factor, which drives trauma-induced neurodegeneration and is lack of efficient tre...

    Authors: Lin Cai, Qiuyuan Gong, Lin Qi, Tongtong Xu, Qian Suo, Xiang Li, Wei Wang, Yao Jing, Dianxu Yang, Zhiming Xu, Fang Yuan, Yaohui Tang, Guoyuan Yang, Jun Ding, Hao Chen and Hengli Tian
    Citation: Cell Communication and Signaling 2022 20:56
    Content type: Research Published on:

  46. Synapses can adapt to changes in the intracerebral microenvironment by regulation of presynaptic neurotransmitter release and postsynaptic neurotransmitter receptor expression following hypoxic ischemia (HI) i...

    Authors: Kexin Li, Meng Lu, Mengxu Cui, Xiaoming Wang and Yang Zheng
    Citation: Cell Communication and Signaling 2022 20:55
    Content type: Research Published on:

  47. The Protein kinase D3 (PKD3) has been implicated in signal transduction downstream of the T cell receptor (TCR). However, its role for the activation of primary T lymphocytes has not been elucidated so far.

    Authors: Jiří Koutník, Verena Neururer, Thomas Gruber, Sebastian Peer, Natascha Hermann-Kleiter, William J. Olson, Verena Labi, Michael Leitges, Gottfried Baier and Kerstin Siegmund
    Citation: Cell Communication and Signaling 2022 20:54
    Content type: Research Published on:

  48. Peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1α (PGC-1α) downregulation in skeletal muscle contributes to insulin resistance and type 2 diabetes mellitus. Here, we examined the effects of e...

    Authors: Marta Montori-Grau, David Aguilar-Recarte, Mohammad Zarei, Javier Pizarro-Delgado, Xavier Palomer and Manuel Vázquez-Carrera
    Citation: Cell Communication and Signaling 2022 20:53
    Content type: Research Published on:

  49. Skin innervation is crucial for normal wound healing. However, the relationship between nerve receptors and wound healing and the intrinsic mechanism remains to be further identified. In this study, we investi...

    Authors: Siyuan Yin, Ru Song, Jiaxu Ma, Chunyan Liu, Zhenjie Wu, Guoqi Cao, Jian Liu, Guang Zhang, Huayu Zhang, Rui Sun, Aoyu Chen and Yibing Wang
    Citation: Cell Communication and Signaling 2022 20:52
    Content type: Research Published on:

  50. Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles originating from different cell compartments. EVs participate in many essential physiological functions and mediate fetal...

    Authors: Mehri Ghafourian, Roya Mahdavi, Zahra Akbari Jonoush, Mahvash Sadeghi, Nooshin Ghadiri, Maryam Farzaneh and Abdolah Mousavi Salehi
    Citation: Cell Communication and Signaling 2022 20:51
    Content type: Review Published on:
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Cell Communication and Signaling

ISSN: 1478-811X