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As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times. Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

Aims and Scope

Cell Communication and Signaling (CCS) is an open access journal that encompasses all basic and translational aspects of cellular communications and signaling pathways in normal and pathological conditions.

Beginning in January of 2019, CCS is pleased to announce their affiliation with the International Cell Death Society

The journal encourages submissions in all aspects of cell death, that include apoptotic and non-apoptotic mechanisms of cell death, cell death in model systems, autophagy, clearance of dying cells, as well as the immunological and pathological consequences of dying cells in the tissue microenvironment. 

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  1. Authors: Katarzyna Pustelny, Katarzyna Kuska, Andrzej Gorecki, Bogdan Musielak, Ewelina Dobosz, Benedykt Wladyka, Joanna Koziel, Anna Czarna, Tad Holak and Grzegorz Dubin

    Content type: Research

News & Updates

13th Annual ÖGMBT Annual Meeting
The 2021 Meeting of the Austrian Association of Molecular Life Sciences and Biotechnology will be held virtually 20th September to 14 October, 2021. For more information and updates, please visit the Meeting Website. 

New Thematic Series open for submissions
Guest Editors Nicole Meisner-Kober and Silja Wessler are welcoming submissions to their new series on Extracellular Vesicles in Infectious Disease. Learn more about the series here

Call for papers

Extracellular vesicles in infectious disease
Edited by Dr. Nicole-Meisner Kober and Dr Silja Wessler
Submission Deadline: March 1, 2022

Stress signaling in infectious disease, inflammation, and cancer
Edited by Xiangya Ding
Submission Deadline: August 1, 2022
Kinases, adaptor proteins, and actin cytoskeleton rearrangements in EMT and cancer

Edited by Dr. Leszek Kotula and Dr. Patrycja Dubielecka-Sczerba
Submission Deadline: December 31, 2021

Submit your manuscript here.

Featured Articles

Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition
In this review article, Ortiz et al. describe some key mechanisms through which the Src family kinases play a critical role in epithelial homeostasis and how their function is essential for the propagation of invasive signals. This article is part of our special thematic series on Kinases, adaptor proteins, and actin cytoskeleton rearrangements in EMT and cancer. 

PML-ll regulates ERK and AKT signal activation and IFNα-induced cell death
Loss of PML protein expression is known to limit apoptosis in many biological contexts. This paper shows that depleting PML isoform II depressed expression of pro-apoptotic genes such as PUMA and TRAIL during an interferon response and potentiated pro-survival ERK and AKT signalling, providing a mechanistic explanation for PML function in apoptosis.

Single-cell analysis reveals cell communication triggered by macrophages associated with the reduction and exhaustion of CD8+ T cells in COVID-19
In He et al.'s article, the authors describe how macrophages driving ligand-receptor crosstalk contributed to the reduction and exhaustion of CD8+ T cells and identify a cytokine panel which may offer selective targets to improve the efficacy of COVID-19 therapy.

Video Bytes are here

At Cell Communication and Signaling, we are passionate about the dissemination of research.

We are pleased to announce that as of the 12th August 2019, all authors whose papers are accepted will receive a Video Byte.

Created by our partners, Research Square, a Video Byte is a 1-2 minute video summary of a paper that will be incorporated into the abstract of the paper and published on the journal website. Authors will also receive a shareable version of their Video Byte.

Editor's profile

New Content Item (1)Raymond Birge, Editor-in-Chief

Raymond Birge, PhD., is a Professor at Rutgers, The State University of New Jersey and member of the New Jersey Medical School Cancer Center. Dr. Birge joined UMDNJ-New Jersey Medical School in 2000 and currently holds a position of Professor and Vice Chair for Research in the Department of Microbiology, Biochemistry and Molecular Biology. Dr. Birge also has joint appointments at the New Jersey Medical School Cancer Center (Newark) and the Cancer Institute of New Jersey (New Brunswick). 

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