Cell Communication and Signaling

Featured article: SOX2 as a novel contributor of oxidative metabolism in melanoma cells

In light of recent research illuminating the role of sex-determining region Y (SRY) BOX2 (SOX2) in cancer, the authors of this article sought to evaluate whether SOX2 modulation is correlated with metabolic shift toward oxidative phosphorylation taking place under acidic tumor microenvironment. Their results suggest that SOX2 does promote an oxidative metabolism that correlates with more aggressive and drug resistant tumor phenotypes with enhanced metastatic ability.

Content type: Research
| 20 February 2019

Cholesterol content in cell membrane maintains surface levels of ErbB2 and confers a therapeutic vulnerability in ErbB2-positive breast cancer

Authors: Jinrui Zhang, Qiong Li, Yueguang Wu, Duchuang Wang, Lu Xu, Yang Zhang, Shanshan Wang, Taishu Wang, Fang Liu, Mohamed Y. Zaky, Shuai Hou, Shuyan Liu, Kun Zou, Haixin Lei, Lijuan Zou, Yingqiu Zhang…
Content type: Research
| 20 February 2019

Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells

Authors: Jaime Santo-Domingo, Antonio Núñez Galindo, Ornella Cominetti, Umberto De Marchi, Pedro Cutillas, Loïc Dayon and Andreas Wiederkehr
Content type: Research
| 19 February 2019

Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells

Authors: Bethany N. Hannafon, Amy L. Gin, Yi-Fan Xu, Matthew Bruns, Cameron L. Calloway and Wei-Qun Ding
Content type: Research
| 13 February 2019

Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation

Authors: Neha Kaushik, Min-Jung Kim, Nagendra Kumar Kaushik, Jae Kyung Myung, Mi-Young Choi, Jae-Hyeok Kang, Hyuk-Jin Cha, Cha-Soon Kim, Seon-Young Nam and Su-Jae Lee
Content type: Research
| 11 February 2019

Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

Authors: Feixia Wang, Yan Jia, Mengmeng Li, Ling Wang, Jiangjuan Shao, Qinglong Guo, Shanzhong Tan, Hai Ding, Anping Chen, Feng Zhang and Shizhong Zheng

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Content type: Research
| 11 October 2014

MicroRNA-188 suppresses G₁/S transition by targeting multiple cyclin/CDK complexes

Authors: Jiangbin Wu, Qing Lv, Jie He, Haoxiang Zhang, Xueshuang Mei, Kai Cui, Nunu Huang, Weidong Xie, Naihan Xu and Yaou Zhang
Content type: Review
| 14 May 2011

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

Authors: Ralf Hass, Cornelia Kasper, Stefanie Böhm and Roland Jacobs
Content type: Review
| 6 April 2016

The new (dis)order in RNA regulation

Authors: Aino I. Järvelin, Marko Noerenberg, Ilan Davis and Alfredo Castello
Content type: Review
| 7 September 2010

Rac and Rho GTPases in cancer cell motility control

Authors: Matteo Parri and Paola Chiarugi
Content type: Review
| 13 September 2011

Interaction of tumor cells with the microenvironment

Authors: Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert and Ralf Hass

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Aims and scope

Cell Communication and Signaling is an open access journal that encompasses all basic and translational aspects of cellular communications and signaling pathways in normal and pathological conditions.

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New Content Item
Beginning in January of 2019, Cell Communication and Signaling is pleased to announce their new affiliation with the Internat ional Cell Death Society.

Upcoming Conferences

New Content Item ICDS 25th Annual Meeting
June 27-30, 2019
New York, New York

The 'International Lecture Series on Disease Biology and Molecular Medicine' has a series of ongoing meetings organized by the Medical Faculty of the Martin-Luther-University Halle-Wittenberg with support from the City of Halle. The International Lecture Series on Disease Biology and Molecular Medicine showcases a wide range of biomedical research areas and fosters collaboration in the scientific community.

Editor's profile

Raymond Birge, Editor-in-Chief

Raymond Birge, PhD., is a Professor at Rutgers, The State University of New Jersey and member of the New Jersey Medical School Cancer Center. Dr. Birge joined UMDNJ-New Jersey Medical School in 2000 and currently holds a position of Professor and Vice Chair for Research in the Department of Microbiology, Biochemistry and Molecular Biology. Dr. Birge also has joint appointments at the New Jersey Medical School Cancer Center (Newark) and the Cancer Institute of New Jersey (New Brunswick).

Cell Communication and Signaling

Featured article: SOX2 as a novel contributor of oxidative metabolism in melanoma cells

Articles

Cholesterol content in cell membrane maintains surface levels of ErbB2 and confers a therapeutic vulnerability in ErbB2-positive breast cancer

Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells

Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells

Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation

Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

MicroRNA-188 suppresses G₁/S transition by targeting multiple cyclin/CDK complexes

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

The new (dis)order in RNA regulation

Rac and Rho GTPases in cancer cell motility control

Interaction of tumor cells with the microenvironment

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Upcoming Conferences

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