Cell Communication and Signaling

Featured article: A role for RASSF1A in tunneling nanotube formation between cells through GEFH1/Rab11 pathway control

Tunneling nanotubes (TNTs) play critical role in coordination of both physiological and pathological conditions between distant cells by allowing transit of the cytoplasmic components. Here, we uncover the unknown role of RASSF1A/GEFH1 signaling as a novel candidate required for TNTs formation through control of Rab11 accumulation and subsequent exosome release. Accordingly, we postulate that targeting TNTs formation in hypermethylated RASSF1A cells, will be a promising therapeutic strategy for preventing intercellular communication in tumor microenvironment.

Content type: Research
| 16 November 2018

Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated β-catenin nuclear accumulation

Authors: Wei Li, Jiu-Zhou Hou, Jie Niu, Zhuo-Qing Xi, Chang Ma, Hua Sun, Chao-Jie Wang, Dong Fang, Qin Li and Song-Qiang Xie
Content type: Research
| 15 November 2018

Four-octyl itaconate activates Keap1-Nrf2 signaling to protect neuronal cells from hydrogen peroxide

Authors: Hua Liu, Yu Feng, Min Xu, Jian Yang, Zhichun Wang and Guangfu Di
Content type: Research
| 8 November 2018

Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway

Authors: Suryakant Niture, Maxwell A. Gyamfi, Habib Kedir, Elena Arthur, Habtom Ressom, Gagan Deep and Deepak Kumar
Content type: Research
| 8 November 2018

USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells

Authors: Aidan P. McCann, Peter Smyth, Francesco Cogo, William J. McDaid, Lai Jiang, Jia Lin, Emma Evergren, Roberta E. Burden, Sandra Van Schaeybroeck, Christopher J. Scott and James F. Burrows
Content type: Review
| 8 November 2018

Perspective on nanochannels as cellular mediators in different disease conditions

Authors: Eshna Jash, Peeyush Prasad, Naveen Kumar, Taruna Sharma, Aaron Goldman and Seema Sehrawat

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Content type: Research
| 11 October 2014

MicroRNA-188 suppresses G₁/S transition by targeting multiple cyclin/CDK complexes

Authors: Jiangbin Wu, Qing Lv, Jie He, Haoxiang Zhang, Xueshuang Mei, Kai Cui, Nunu Huang, Weidong Xie, Naihan Xu and Yaou Zhang
Content type: Review
| 14 May 2011

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

Authors: Ralf Hass, Cornelia Kasper, Stefanie Böhm and Roland Jacobs
Content type: Review
| 6 April 2016

The new (dis)order in RNA regulation

Authors: Aino I. Järvelin, Marko Noerenberg, Ilan Davis and Alfredo Castello
Content type: Review
| 7 September 2010

Rac and Rho GTPases in cancer cell motility control

Authors: Matteo Parri and Paola Chiarugi
Content type: Review
| 13 September 2011

Interaction of tumor cells with the microenvironment

Authors: Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert and Ralf Hass

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Cell Communication and Signaling is an open access journal that encompasses all basic and translational aspects of cellular communications and signaling pathways in normal and pathological conditions.

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Dec 8-12, 2018
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June 27-30, 2019
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The 'International Lecture Series on Disease Biology and Molecular Medicine' has a series of ongoing meetings organized by the Medical Faculty of the Martin-Luther-University Halle-Wittenberg with support from the City of Halle. The International Lecture Series on Disease Biology and Molecular Medicine showcases a wide range of biomedical research areas and fosters collaboration in the scientific community.

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Editor's profile

Raymond Birge, Editor-in-Chief

Raymond Birge, PhD., is a Professor at Rutgers, The State University of New Jersey and member of the New Jersey Medical School Cancer Center. Dr. Birge joined UMDNJ-New Jersey Medical School in 2000 and currently holds a position of Professor and Vice Chair for Research in the Department of Microbiology, Biochemistry and Molecular Biology. Dr. Birge also has joint appointments at the New Jersey Medical School Cancer Center (Newark) and the Cancer Institute of New Jersey (New Brunswick).

Cell Communication and Signaling

Featured article: A role for RASSF1A in tunneling nanotube formation between cells through GEFH1/Rab11 pathway control

Articles

Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated β-catenin nuclear accumulation

Four-octyl itaconate activates Keap1-Nrf2 signaling to protect neuronal cells from hydrogen peroxide

Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway

USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells

Perspective on nanochannels as cellular mediators in different disease conditions

MicroRNA-188 suppresses G₁/S transition by targeting multiple cyclin/CDK complexes

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

The new (dis)order in RNA regulation

Rac and Rho GTPases in cancer cell motility control

Interaction of tumor cells with the microenvironment

Aims and scope

Upcoming Conferences

Other sponsorships

Editor's profile

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