In this recent paper, Adah et al. sought to reveal the pathways by which the malaria causing parasite Plasmodium promotes lung cancer immunity in a murine model. They found that infection significantly reduced myeloid-derived suppressor cells and regulatory T cells owing to the downregulation of recruiting molecules and the blocking of cellular activation pathways. Notably, the infected cells contained high levels of perforin and granzyme B while inhibiting PD-1 expression.
Featured Article: Plasmodium infection inhibits the expansion and activation of MDSCs and Tregs in the tumor microenvironment in a murine Lewis lung cancer model
Aims and Scope
Cell Communication and Signaling is an open access journal that encompasses all basic and translational aspects of cellular communications and signaling pathways in normal and pathological conditions.
Featured Collection
25th Anniversary of the International Cell Death Society Collection
Curated by Editor-in-Chief Raymond Birge, we're celebrating the 25th anniversary of the ICDS with a collection highlighting the most important Cell Death papers published in Cell Communication and Signaling in the last decade.
Upcoming Conferences
ICDS 25th Annual Meeting
June 27-30, 2019
New York, New York
The 11th Annual Österreichische Gesellschaft für Molekulare Biowissenschaften und Biotechnologie (ÖGMBT) Meeting "Inside the World of Biomolecules" is taking place on 16th-18th September at the Wyndham Grand Salzburg Conference Centre in Salzburg.
The ÖGMBT Annual Meeting welcomes scientists from all research areas and all career levels and is an opportunity to connect with the brightest minds in life sciences.
Editor's profile
Raymond Birge, Editor-in-Chief
Raymond Birge, PhD., is a Professor at Rutgers, The State University of New Jersey and member of the New Jersey Medical School Cancer Center. Dr. Birge joined UMDNJ-New Jersey Medical School in 2000 and currently holds a position of Professor and Vice Chair for Research in the Department of Microbiology, Biochemistry and Molecular Biology. Dr. Birge also has joint appointments at the New Jersey Medical School Cancer Center (Newark) and the Cancer Institute of New Jersey (New Brunswick).
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Annual Journal Metrics
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Speed
40 days to first decision for reviewed manuscripts only
23 days to first decision for all manuscripts
96 days from submission to acceptance
16 days from acceptance to publication
Citation Impact
5.324 - 2-year Impact Factor
4.397 - 5-year Impact Factor
1.116 - Source Normalized Impact per Paper (SNIP)
2.211 - SCImago Journal Rank (SJR)
Usage
307,679 downloads
182 Altmetric mentions
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