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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Frizzled class receptor 5 contributes to ovarian cancer chemoresistance through aldehyde dehydrogenase 1A1

Fig. 5

FZD5 endows OC cells with chemoresistance. A Viability of OC cells 48 h after treatment with cisplatin analyzed by CCK8 assay (mean ± SD, n = 3). B Viability of OC cells 48 h after treatment with olaparib analyzed by CCK8 assay (mean ± SD, n = 3). C Mammosphere formation of OVCAR3 cells treated with or without cisplatin (10 µM) (mean ± SD, n = 3). D Apoptosis of OVCAR3 cells treated with or without cisplatin (10 µM) detected by flow cytometry (mean ± SD, n = 3). E, F Growth curves of OVCAR3-xenograft tumors treated with or without cisplatin (5 mg/kg) (mean ± SD, n = 5)

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Cell Communication and Signaling

ISSN: 1478-811X