Table 2 Univariate and multivariate analyses evaluating the association between covariates and DFS
From: The Janus-faced role of TRPM2-S in retroperitoneal liposarcoma via increasing ROS levels
Clinicopathological characteristics | Univariate analysis HR (95% CI) | P value | Multivariate analysis HR (95% CI) | P value |
|---|---|---|---|---|
Gender | Â | Â | Â | Â |
Male | Reference | Â | Â | Â |
Female | 1.21 (0.60–2.42) | 0.60 |  |  |
Age (years) | Â | Â | Â | Â |
≤ 55 | Reference |  |  |  |
> 55 | 1.87 (0.90–3.86) | 0.09 | 1.30 (0.60–2.82) | 0.50 |
Tumor number | Â | Â | Â | Â |
Single | Reference | Â | Â | Â |
Multiple | 1.37 (0.59–3.18) | 0.46 |  |  |
Tumor size (cm) | Â | Â | Â | Â |
< 10 | Reference |  |  |  |
10–20 | 1.02 (0.44–2.39) | 0.96 |  |  |
≥ 20 | 0.63 (0.25–1.58) | 0.32 |  |  |
Histological Subtype | Â | Â | Â | Â |
Well-differentiated | Reference | Â | Â | Â |
Dedifferentiated | 3.79 (1.40–10.23) |  < 0.01 | 3.02 (1.06–8.66) | 0.04 |
Myxoid/round cell | – |  |  |  |
Pleomophic | 4.00 (0.94–17.16) | 0.06 | 3.17 (0.69–14.63) | 0.14 |
TRPM2-L | Â | Â | Â | Â |
Low | Reference | Â | Â | Â |
High | 1.81 (0.79–4.15) | 0.160 |  |  |
TRPM2-L and TRPM2-S | Â | Â | Â | Â |
Low | Reference | Â | Â | Â |
High | 0.42 (0.20–0.88) | 0.021 | 0.63 (0.29–1.37) | 0.24 |