Fig. 6
From: The Janus-faced role of TRPM2-S in retroperitoneal liposarcoma via increasing ROS levels
NAC appeased the TRPM2-S enhanced apoptosis of RPLS cells under oxidative stress. a–e Representative images of flow cytometry for apoptosis, including 94T778-Control (a), 94T778-Control-H2O2 (b), 94T778-TRPM2-S (c), 94T778-TRPM2-S-H2O2 (d), 94T778-TRPM2-S-H2O2-NAC (e). f Analysis of apoptosis rate of 94T778 cell. g–k Representative images of flow cytometry for apoptosis, including SW872-Control (g), SW872-Control-H2O2 (h), SW872-TRPM2-S (i), SW872-TRPM2-S-H2O2 (j), SW872-TRPM2-S-H2O2-NAC (k). l Analysis of apoptosis rate of SW872 cell. m Western blotting revealed that cleaved caspase 3 was upregulated in TRPM2-S-H2O2 RPLS cells but was downregulated in TRPM2-S-H2O2-NAC RPLS cells compared with control-H2O2 and TRPM2-S-H2O2 RPLS cells respectively