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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway

Fig. 7Fig. 7

The AKT kinase inhibitor (HY-10249A) reverses the effect of KOR knockdown on ECM degradation and actin cytoskeletal rearrangement. A. HY-10249A reversed the effect of KOR knockdown on inducing MMP2 secretion. B. HY-10249A reversed the effect of KOR knockdown on invadopodia formation. C. HY-10249A reversed the effect of KOR knockdown on actin cytoskeletal rearrangement

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