Fig. 7From: RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathwayThe AKT kinase inhibitor (HY-10249A) reverses the effect of KOR knockdown on ECM degradation and actin cytoskeletal rearrangement. A. HY-10249A reversed the effect of KOR knockdown on inducing MMP2 secretion. B. HY-10249A reversed the effect of KOR knockdown on invadopodia formation. C. HY-10249A reversed the effect of KOR knockdown on actin cytoskeletal rearrangementBack to article page