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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway

Fig. 4Fig. 4

KOR downregulation enhances ECM degradation and mediates actin cytoskeletal rearrangement. A Substrate gel zymography showed that KOR knockdown induced MMP2 secretion. B 3D cell culture indicated that KOR knockdown enhanced invadopodia information. C Immunofluorescence imaging showed that down-regulated KOR mediated actin cytoskeleton rearrangement, especially in extended filopodia

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Cell Communication and Signaling

ISSN: 1478-811X