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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway

Fig. 1

KOR expression might be related with ESCC progression. A Different expression level of OPRK1 (KOR gene) in tumor and adjacent normal tissue. The expression level of OPRK1 in adjacent normal tissue was higher than that of tumor tissue (P = 0.04). B Kaplan–Meier survival curves of patients classified into high- and low-expression KOR groups. Compared with the high KOR expression group, ESCC patients with low KOR expression had a lower survival time (P = 0.03). C Relative expression of KOR was detected in five ESCC cell lines by western blotting and KOR expression was normalized to GAPDH. D–E KYSE150 and KYSE410 cells showed more active proliferation and invasion characteristics than KYSE30 and KYSE180 cells

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Cell Communication and Signaling

ISSN: 1478-811X