Skip to main content

Correction to: Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression

The Original Article was published on 15 February 2021

Correction to: Cell Commun Signal (2021) 19:18 https://doi.org/10.1186/s12964-020-00679-7

Following publication of the original article [1], the authors identified the following error. Due to the improper labelling of cell scratch images during the collection of experimental data, the upper and lower right images of scratch assay in Fig. 5i (i.e. the 0 h and 24 h scratch of cells overexpressing HRD1 and PFKP) were misused, though not affecting the results and scientific conclusions of the original article. The authors apologize for the mistakes and have corrected the error by replacing them with the proper cell scratch images. The updated Fig. 5 is shown as below.

Fig. 5
figure 5

HRD1 inhibited aerobic glycolysis, growth, migration, and invasion of breast cancer cells via PFKP downregulation. MDA-MB-231 cells stably expressing HRD1 were infected with a lentivirus for PFKP for 48 h. a Western blotting was performed. b Glucose uptake was determined by measuring uptake of 2-NBDG using flow cytometry. c Glucose concentration in the medium was measured using the Amplex Red glucose/glucose oxidase assay kit. d Lactate levels in the extracellular medium and the intracellular lactate levels in the cell lysates were measured using the lactate assay kit. e ATP concentration was measured using an ATP assay kit. f Extracellular acidification rate (ECAR) was measured using Seahorse XF96 Flux Analyzer. g MDA-MB-231 cells stably expressing HRD1 were infected with a lentivirus for PFKP for 72 h, and then cell proliferation was measured using CCK-8 assays. h MDA-MB-231 cells stably expressing HRD1 were infected with a lentivirus for PFKP for 3 weeks, and then colony-formation assay were performed. i, j MDA-MB-231 cells stably expressing HRD1 were infected with a lentivirus for PFKP for 48 h, and then the migration and invasion assays were performed

Reference

  1. Fan Y, Wang J, Xu Y, et al. Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression. Cell Commun Signal. 2021;19:18. https://doi.org/10.1186/s12964-020-00679-7.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Feng Jin or Dongming Su.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Fan, Y., Wang, J., Xu, Y. et al. Correction to: Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression. Cell Commun Signal 19, 111 (2021). https://doi.org/10.1186/s12964-021-00803-1

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s12964-021-00803-1