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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: STING protects against cardiac dysfunction and remodelling by blocking autophagy

Fig. 2

STING overexpression suppressed cardiac hypertrophy and fibrosis in vivo A Representative western blot of STING in wild type mice and STING TG mice (n = 6). BD Statistical results of the heart weight (HW)/body weight (BW), lung weight (LW)/BW and HW/tibia length (TL) (n = 12). E Representative image of the heart with H&E staining and statistical results of cross-sectional area (n = 6). F The mRNA level of hypertrophic markers (ANP) (n = 6). G Representative image of the heart with Picrosirius Red (PSR) staining and statistical results of perivascular and interstitial fibrosis (n = 6). HK The mRNA level of fibrotic markers (Fibronectin, Ctgf, Collagen1 and Collagen3) (n = 6), *P < 0.05 vs the Sham + WT group, #P < 0.05 vs the AB + WT group

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