Fleming I. Molecular mechanisms underlying the activation of eNOS. Pflugers Arch. 2010;459:793–806.
Article
CAS
PubMed
Google Scholar
Siragusa M, Fleming I. The eNOS signalosome and its link to endothelial dysfunction. Pflugers Arch. 2016;468:1125–37.
Article
CAS
PubMed
Google Scholar
Koesling D, Friebe A. Soluble guanylyl cyclase: structure and regulation. Rev Physiol Biochem Pharmacol. 1999;135:41–65.
CAS
PubMed
Google Scholar
Martin E, Berka V, Tsai AL, Murad F. Soluble guanylyl cyclase: the nitric oxide receptor. Methods Enzymol. 2005;396:478–92.
Article
CAS
PubMed
Google Scholar
Tsai AL, Berka V, Sharina I, Martin E. Dynamic ligand exchange in soluble guanylyl cyclase (sGC): implications for sGC regulation and desensitization. J Biol Chem. 2011;286:43182–92.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cortese-Krott MM, Rodriguez-Mateos A, Sansone R, Kuhnle GG, Thasian-Sivarajah S, Krenz T, Horn P, Krisp C, Wolters D, Heiss C, et al. Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease. Blood. 2012;120:4229–37.
Article
CAS
PubMed
Google Scholar
Srihirun S, Sriwantana T, Unchern S, Kittikool D, Noulsri E, Pattanapanyasat K, Fucharoen S, Piknova B, Schechter AN, Sibmooh N. Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation. PLoS One. 2012;7:e30380.
Article
CAS
PubMed
PubMed Central
Google Scholar
Corti P, Xue J, Tejero J, Wajih N, Sun M, Stolz DB, Tsang M, Kim-Shapiro DB, Gladwin MT. Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells. Proc Natl Acad Sci U S A. 2016;113:8538–43.
Article
CAS
PubMed
Google Scholar
Akrawinthawong K, Park JW, Piknova B, Sibmooh N, Fucharoen S, Schechter AN. A flow cytometric analysis of the inhibition of platelet reactivity due to nitrite reduction by deoxygenated erythrocytes. PLoS One. 2014;9:e92435.
Article
PubMed
PubMed Central
Google Scholar
Anand A, Feffer SE. Hematocrit and bleeding time: an update. South Med J. 1994;87:299–301.
Article
CAS
PubMed
Google Scholar
Boneu B, Fernandez F. The role of the hematocrit in bleeding. Transfus Med Rev. 1987;1:182–5.
Article
CAS
PubMed
Google Scholar
Silvain J, Abtan J, Kerneis M, Martin R, Finzi J, Vignalou JB, Barthelemy O, O’Connor SA, Luyt CE, Brechot N, et al. Impact of red blood cell transfusion on platelet aggregation and inflammatory response in anemic coronary and noncoronary patients: the TRANSFUSION-2 study (impact of transfusion of red blood cell on platelet activation and aggregation studied with flow cytometry use and light transmission aggregometry). J Am Coll Cardiol. 2014;63:1289–96.
Article
PubMed
Google Scholar
Kumbhani DJ, Bhatt DL. Platelet activation: yet another strike against routine TRANSFUSION. Eur Heart J. 2010;31:2712–4.
Article
PubMed
Google Scholar
Jia L, Bonaventura C, Bonaventura J, Stamler JS. S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control. Nature. 1996;380:221–6.
Article
CAS
PubMed
Google Scholar
Tejero J, Basu S, Helms C, Hogg N, King SB, Kim-Shapiro DB, Gladwin MT. Low NO concentration dependence of reductive nitrosylation reaction of hemoglobin. J Biol Chem. 2012;287:18262–74.
Article
CAS
PubMed
PubMed Central
Google Scholar
Basu S, Grubina R, Huang J, Conradie J, Huang Z, Jeffers A, Jiang A, He X, Azarov I, Seibert R, et al. Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin. Nat Chem Biol. 2007;3:785–94.
Article
CAS
PubMed
Google Scholar
Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, Yang BK, Waclawiw MA, Zalos G, Xu X, et al. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med. 2003;9:1498–505.
Article
CAS
PubMed
Google Scholar
Isbell TS, Sun CW, Wu LC, Teng X, Vitturi DA, Branch BG, Kevil CG, Peng N, Wyss JM, Ambalavanan N, et al. SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation. Nat Med. 2008;14:773–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Schwab DE, Stamler JS, Singel DJ. Nitrite-methemoglobin inadequate for hypoxic vasodilation. Nat Chem Biol. 2009;5:366. author reply 367.
Article
CAS
PubMed
Google Scholar
Bohmer A, Beckmann B, Sandmann J, Tsikas D. Doubts concerning functional endothelial nitric oxide synthase in human erythrocytes. Blood. 2012;119:1322–3.
Article
PubMed
Google Scholar
Hall CN, Garthwaite J. What is the real physiological NO concentration in vivo? Nitric Oxide. 2009;21:92–103.
Article
CAS
PubMed
PubMed Central
Google Scholar
Azarov I, Huang KT, Basu S, Gladwin MT, Hogg N, Kim-Shapiro DB. Nitric oxide scavenging by red blood cells as a function of hematocrit and oxygenation. J Biol Chem. 2005;280:39024–32.
Article
CAS
PubMed
Google Scholar
Azarov I, Liu C, Reynolds H, Tsekouras Z, Lee JS, Gladwin MT, Kim-Shapiro DB. Mechanisms of slower nitric oxide uptake by red blood cells and other hemoglobin-containing vesicles. J Biol Chem. 2011;286:33567–79.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gambaryan S, Subramanian H, Kehrer L, Mindukshev I, Sudnitsyna J, Reiss C, Rukoyatkina N, Friebe A, Sharina I, Martin E, Walter U. Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis. Cell Commun Signal. 2016;14:16.
Article
PubMed
PubMed Central
Google Scholar
Munzel T, Feil R, Mulsch A, Lohmann SM, Hofmann F, Walter U. Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected]. Circulation. 2003;108:2172–83.
Article
PubMed
Google Scholar
Bonello L, Camoin-Jau L, Arques S, Boyer C, Panagides D, Wittenberg O, Simeoni MC, Barragan P, Dignat-George F, Paganelli F. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study. J Am Coll Cardiol. 2008;51:1404–11.
Article
CAS
PubMed
Google Scholar
Bonello L, Paganelli F, Arpin-Bornet M, Auquier P, Sampol J, Dignat-George F, Barragan P, Camoin-Jau L. Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events. J Thromb Haemost. 2007;5:1630–6.
Article
CAS
PubMed
Google Scholar
Schwarz UR, Geiger J, Walter U, Eigenthaler M. Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets--definition and detection of ticlopidine/clopidogrel effects. Thromb Haemost. 1999;82:1145–52.
CAS
PubMed
Google Scholar
Walter U, Gambaryan S. cGMP and cGMP-dependent protein kinase in platelets and blood cells. Handb Exp Pharmacol. 2009;191:533–48.
Article
CAS
PubMed
Google Scholar
Gambaryan S, Tsikas D. A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from L-arginine or nitrite? Amino Acids. 2015;47:1779–93.
Article
CAS
PubMed
Google Scholar
Singel DJ, Stamler JS. Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol. 2005;67:99–145.
Article
CAS
PubMed
Google Scholar
Diesen DL, Hess DT, Stamler JS. Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal. Circ Res. 2008;103:545–53.
Article
CAS
PubMed
PubMed Central
Google Scholar
Robinson JM, Lancaster Jr JR. Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide: mechanism(s) and physiologic versus pathophysiologic relevance. Am J Respir Cell Mol Biol. 2005;32:257–61.
Article
CAS
PubMed
Google Scholar
Kulandavelu S, Balkan W, Hare JM. Regulation of oxygen delivery to the body via hypoxic vasodilation. Proc Natl Acad Sci U S A. 2015;112:6254–5.
Article
CAS
PubMed
PubMed Central
Google Scholar