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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein

Fig. 9

Signaling consequences of dimerization and oligomerization by the tandem SAM domains of CASKIN2. In its oligomeric form, CASKIN2 would provide a vast array of interaction sites with enhanced avidity for many proteins through its available intrinsically unstructured regions and ankyrin repeats. In its dimeric form, CASKIN2 could fulfill a classic adaptor role bringing together protein partners that potentially depend on dimerization themselves for coupling and activation

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