Fig. 9From: A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding proteinSignaling consequences of dimerization and oligomerization by the tandem SAM domains of CASKIN2. In its oligomeric form, CASKIN2 would provide a vast array of interaction sites with enhanced avidity for many proteins through its available intrinsically unstructured regions and ankyrin repeats. In its dimeric form, CASKIN2 could fulfill a classic adaptor role bringing together protein partners that potentially depend on dimerization themselves for coupling and activationBack to article page