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Figure 3 | Cell Communication and Signaling

Figure 3

From: Ways and means of coping with uncertainties of the relationship of the genetic blue print to protein structure and function in the cell

Figure 3

Illustration of the variety of different multimeric assemblies of horizontal cytokine-receptors on ligand binding and activation. hGH = human growth hormone. EP0 = erythropoetin. GCSF = Granulocyte Colony-stimulating factor. FGF = Fibroblast growth factor. IL-4 = Interleukin 4. TNF = Tumour necrosis factor. This figure is originally reproduced with permission of the authors R. M. Stroud and J. A. Wells (2004) and the AAAS from <Mechanistic Diversity of Cytokine Receptor Signalling Across Cell Membranes>, and the journal, Science STKE.2004.Re: 7, pps: 1-17, and is shown in my forthcoming book in German: <Von Molekülen zu Zellen. 100 Jahre experimentelle Biologie. Betrachtungen eines Biochemikers>. It is reproduced here with permission of the GNT Verlag für Geschichte der Naturwissenschaften und der Technik. Diepholz. Stuttgart, Berlin.

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