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Erratum to: The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells

The Original Article was published on 24 April 2013


In the original paper published [1], there is a mistake in Figure 4. Figure 4D and Figure 4E are the same, but Figure 4E should have been different (the figures show two different cell lines). Figure 1 in this correction article is the correct version of Figure 4 from the original article [1]. The figure legend does not need to be changed.

Figure 1

LPA 3 , but not or to lesser extent LPA 1 , LPA 2 , and LPA 4 , mediated the LPA-dpYAP effect. A, OVCA433 (a) and OVCAR5 (c) cells were starved and pretreated with Ki16425 (10 μM) for 1 hr prior to treatment with LPA (10 μM, 2 hr). pYAP was analyzed by Western blot. (b) The effect of Ki16425 on LPA (10 μM, 2 hr)-induced YAP nuclear translocation in OVCA433 cells. Green: YAP; red: DAPI. Representative results are shown. B, (a) The mRNA levels of LPA receptors after siRNA-treatment in OVCAR433 cells were determined by quantitative real-time PCR. Normalized expression values are given as percentage of control siRNA treated samples (means ± SD of three independent experiments). *** P < 0.001. (b) LPA (10 μM, 2 hr)-induced dpYAP effects were determined in LPA receptor specific siRNA-treated cells (48 hr post-transfection). (c) Quantitation of Western blots from (b) presented as fold decrease of pYAP after LPA stimulation compared to unstimulated controls. The data are means ± SD from three independent experiments. * P < 0.05. C, D and E, Cells were pretreated with PTX (100 ng/mL, 16 hr) or transfected with different dn plasmids for 48 hr, starved and then treated with LPA (10 μM, 2 hr). Cell lysates were analyzed by Western blot. Representative results are shown.


  1. 1.

    Cai H, Xu Y: The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells. Cell Communication and Signaling. 2013, 11: 31-10.1186/1478-811X-11-31. doi:10.1186/1478-811X-11-31. PMID: 23618389

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Correspondence to Yan Xu.

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The online version of the original article can be found at 10.1186/1478-811X-11-31

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Cai, H., Xu, Y. Erratum to: The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells. Cell Commun Signal 11, 92 (2013).

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