Figure 6
From: When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling
Schematic diagram and simulations of network motif 4. (a) Motif 4’s interaction scheme. (b) Sustained oscillations for total active S (S* + pS*) and active E3 when the ubiquitinated S moieties are negligibly degraded (left), and damped oscillations when the degradation becomes non-negligible (right). Parameters used are given in the SI.