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  1. The chondrosarcoma-derived HCS-2/8 has been known to be an excellent model of human articular chondrocytes. By mimicking the arthritic conditions through the treatment of HCS-2/8 cells with cytokines, we estim...

    Authors: Norifumi H Moritani, Satoshi Kubota, Toshio Sugahara and Masaharu Takigawa
    Citation: Cell Communication and Signaling 2005 3:6
    Content type: Research Published on:

  2. The human cysteine rich protein 61 (CYR61, CCN1) as well as the other members of the CCN family of genes play important roles in cellular processes such as proliferation, adhesion, migration and survival. Thes...

    Authors: Norbert Schutze, Ulrich Noth, Jutta Schneidereit, Christian Hendrich and Franz Jakob
    Citation: Cell Communication and Signaling 2005 3:5
    Content type: Research Published on:

  3. Agnogenic myeloid metaplasia (AMM) is one of the Philadelphia chromosome negative myeloproliferative disorder and is diagnosed by hyperplasia of atypical megakaryocytes, hepatosplenomegaly, extramedullary hema...

    Authors: Kirugaval C Hemavathy, Kathir Suppiah, Gazala Hashmi, Allan D Novetsky and Jen C Wang
    Citation: Cell Communication and Signaling 2005 3:4
    Content type: Research Published on:

  4. During endochondral bone formation, the hypertrophy of chondrocytes is accompanied by selective expression of several genes including type X collagen and alkaline phosphatase. This expression is stimulated by ...

    Authors: Gwendolen C Reilly, Eleanor B Golden, Giovi Grasso-Knight and Phoebe S Leboy
    Citation: Cell Communication and Signaling 2005 3:3
    Content type: Research Published on:

  5. A treatment to remove vascular blockages, angioplasty, can cause damage to the vessel wall and a subsequent abnormal wound healing response, known as restenosis. Vascular smooth muscle cells (VSMC) lining the ...

    Authors: Karl Kingsley and George E Plopper
    Citation: Cell Communication and Signaling 2005 3:2
    Content type: Research Published on:

  6. The ciliary neurotrophic factor (CNTF) receptor is composed of two signalling receptor chains, gp130 and the leukaemia inhibitory factor receptor, associated with a non-signalling CNTF binding receptor α compo...

    Authors: Béatrice de Bovis, Damien Derouet, Jean-François Gauchat, Greg Elson, Hugues Gascan and Odile deLapeyrière
    Citation: Cell Communication and Signaling 2005 3:1
    Content type: Research Published on:

  7. To study the cellular distribution of CCN3(NOV) and to determine if the carboxyterminus of CCN3 is hidden or masked due to high affinity interactions with other partners. CCN3 was detected using affinity purif...

    Authors: Stanimir Kyurkchiev, Herman Yeger, Anne-Marie Bleau and Bernard Perbal
    Citation: Cell Communication and Signaling 2004 2:9
    Content type: Research Published on:

  8. In the early 1990's, a new cell signaling pathway was described. This new paradigm, now known as the JAK/STAT pathway, has been extensively investigated in immune-type cells in response to interferons and inte...

    Authors: Andrew C Dudley, David Thomas, James Best and Alicia Jenkins
    Citation: Cell Communication and Signaling 2004 2:8
    Content type: Review Published on:

  9. In this article we briefly review the reasons and advantages that underly our publisher's decision to introduce article-processing charges (APC) for manuscripts submitted to Cell Communication and Signaling. The ...

    Authors: Bernard Perbal
    Citation: Cell Communication and Signaling 2004 2:7
    Content type: Editorial Published on:

  10. The endozepine triakontatetraneuropeptide (TTN) induces intracellular calcium ([Ca++]i) changes followed by activation in human polymorphonuclear leukocytes (PMNs). The present study was undertaken to investigate...

    Authors: Franca Marino, Marco Cosentino, Marco Ferrari, Simona Cattaneo, Giuseppina Frigo, Anna M Fietta, Sergio Lecchini and Gian Mario Frigo
    Citation: Cell Communication and Signaling 2004 2:6
    Content type: Research Published on:

  12. In human and non-human primates, migratory trophoblasts penetrate the uterine epithelium, invade uterine matrix, and enter the uterine vasculature. Invasive trophoblasts show increased expression of β1 integri...

    Authors: Twanda L Thirkill, Sonia R Hendren, Arlen Soghomonians, Natalie F Mariano, Abdul I Barakat and Gordon C Douglas
    Citation: Cell Communication and Signaling 2004 2:4
    Content type: Research Published on:

  13. The immunosuppressive agent cyclosporin A (CsA), a calcineurin inhibitor which blocks T cell activation has provided the pharmacologic foundation for organ transplantation. CsA exerts additional effects on non...

    Authors: Parvaneh Rafiee, Jan Heidemann, Hitoshi Ogawa, Nathan A Johnson, Pamela J Fisher, Mona S Li, Mary F Otterson, Christopher P Johnson and David G Binion
    Citation: Cell Communication and Signaling 2004 2:3
    Content type: Research Published on:

  14. Connexin43 (Cx43) is an integral membrane protein that forms intercellular channels called gap junctions. Intercellular communication in the eye lens relies on an extensive network of gap junctions essential f...

    Authors: Henrique Girão, Steve Catarino and Paulo Pereira
    Citation: Cell Communication and Signaling 2004 2:2
    Content type: Research Published on:

  15. In the present study we have analyzed the mechanisms of calcium entry and mobilization in platelets obtained from rats chronically treated with the nitric oxide synthesis inhibitor, N-nitro L-arginine methyl e...

    Authors: David Iyú, Noemí M Atucha, Concepción Martínez-Prieto, M Clara Ortiz and Joaquín García-Estañ
    Citation: Cell Communication and Signaling 2004 2:1
    Content type: Research Published on:

  16. Vascular smooth muscle cell (VSMC) hyperplasia plays an important role in both chronic and acute vascular pathologies including atherosclerosis and restenosis. Considerable work has focused on the mechanisms r...

    Authors: Andrew C Lake and John J Castellot Jr
    Citation: Cell Communication and Signaling 2003 1:5
    Content type: Research Published on:

  17. Guanylyl cyclase-B (GC-B; NPR-B), the receptor for C-type natriuretic peptide (CNP) is rapidly and effectively desensitized by a factor(s) in serum. Given the potential importance of this receptor in remodelin...

    Authors: Ted D Chrisman, Dorenda T Perkins and David L Garbers
    Citation: Cell Communication and Signaling 2003 1:4
    Content type: Research Published on:

  18. All forms of communication between human beings have long been recognized as a requirement for reciprocal understanding, transfer of knowledge, and productive development of societies. This also applies to liv...

    Authors: Bernard Perbal
    Citation: Cell Communication and Signaling 2003 1:3
    Content type: Editorial Published on:

  20. The CCN family of genes consists presently of six members in human (CCN1-6) also known as Cyr61 (Cystein rich 61), CTGF (Connective Tissue Growth Factor), NOV (Nephroblastoma Overexpressed gene), WISP-1, 2 and...

    Authors: Alain Lombet, Nathalie Planque, Anne-Marie Bleau, ChangLong Li and Bernard Perbal
    Citation: Cell Communication and Signaling 2003 1:1
    Content type: Review Published on:
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