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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: pathogenesis and therapeutic implications

Fig. 3

Oxidative stress response in ECs. Reactive oxygen species (ROS) within ECs primarily originate from mitochondria, NADPH oxidases (NOXs), endothelial nitric oxide synthase (eNOS) uncoupling, and xanthine oxidase (XO). The generation of ROS through various pathways results in the upregulation of ROS expression in ECs, leading to mechanical cell death and disruption of intercellular junctions

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Cell Communication and Signaling

ISSN: 1478-811X