Fig. 8
From: Interleukin-4 protects retinal ganglion cells and promotes axon regeneration
Recombinant IL-4 protein reduced RGC cell death caused by ONC injury. A: Immunofluorescence staining of retinal ganglion cells in the negative control group, vehicle group and IL-4 group on day 7 and day 14 showed that the density of RGCs in the rIL-4 group was higher than that in the vehicle group at the same treatment time. B: Schematic diagram of the RGC counting method. The calculation method of the relative RGC survival rate was similar to the method of the NMDA model. C: Relative RGC survival rate of each group. The relative RGC survival rate of the rIL-4 group was greater than that of the vehicle group with the same treatment time. n = 9 eyes per group, ** indicates p < 0.01, **** indicates p < 0.001