Fig. 1
From: Tumor-derived miR-6794-5p enhances cancer growth by promoting M2 macrophage polarization
MiR-6794-5p is upregulated within Bcl-w-derived exosomes. A Heatmap showing expressed exosomal miRNAs between vector and Bcl-w. B A549 cells were transfected with the negative control (NC), miR-1343-5p, miR-2861, miR-6794-5p, and miR-122-5p mimics, respectively. The mRNA expression levels of Twist, Zeb1, N-cad, and Oct4 by each miRNA were measured by qRT-PCR. The values were normalized to GAPDH. C Expression level of miR-6794-5p in exosomes isolated from conditioned media from Bcl-w-overexpressing A549 cells. D miR-6794-5p expression levels in Bcl-w overexpressing U251 and A549 cells. E The expression of miR-6794-5p in plasma of normal and patients with lung cancer (normal, n = 29; lung cancer, n = 24) was analyzed by qRT-PCR. The values were normalized to U6. Data are presented as mean ± SD after triplicate. *P< 0.05; **P<0.01; ***P<0.001. Student's t-test