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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: The enhanced antitumor activity of bispecific antibody targeting PD-1/PD-L1 signaling

Fig. 1

Bispecific antibodies (BsAbs) enhance tumor killing by guiding various effector cells to tumor cells in a non-MHC-restricted manner. BsAbs facilitate the interaction between T cells and tumor cells, triggering a sequence of events leading to T cell activation. The primary mechanism employed by activated T cells in cancer cell lysis involves Granzyme-B and perforin (Adapted from “Bispecific Antibody Mechanism of Action”, by BioRender 2023)

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Cell Communication and Signaling

ISSN: 1478-811X