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Fig. 10 | Cell Communication and Signaling

Fig. 10

From: Investigating the therapeutic effects and mechanisms of Carthamus tinctorius L.-derived nanovesicles in atherosclerosis treatment

Fig. 10

The effect of miR166a-3p on atherosclerosis in ApoE-/- mice. A The levels of serum TG, TC and LDL-C were measured in six mice per group. B The levels of serum IL-1β, IL-6, and CXCL12 were measured in six mice per group. C Representative images of oil-red-O staining of aortic trees in ApoE-/- mice were obtained. D Statistical analyses of plaque area in the aortic trees were performed using samples from five mice per group. E Representative images of oil-red-O staining of aortic roots in ApoE-/- mice were obtained. Scale bar: 500 μm. F Statistical analyses of plaque area in the aortic roots were performed using samples from six mice per group. Data are presented as the means ± SD. Significance levels are indicated as *P < 0.05, **P < 0.01, ***P < 0.001, or ns for not significant

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