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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Investigating the therapeutic effects and mechanisms of Carthamus tinctorius L.-derived nanovesicles in atherosclerosis treatment

Fig. 1

Comprehensive analysis of CDNVs: contents, miRNA profiling, and identification. A A representative transmission electron microscopy (TEM) image of purified CDNVs, with a scale bar representing 200 nm. B The average size of CDNVs was characterized by NanoSight analysis. C Immunoblotting images of exosomal markers in CDNVs were obtained. The three bands representing protein samples extracted from three batches of CDNVs. D The surface zeta potential of CDNVs was determined. E The proteins extracted from CDNVs were separated using SDS‒PAGE and stained using Coomassie blue dye. F The RNAs extracted from CDNVs were identified by electrophoresis using a 1.2% polyacrylamide gel. G UHPLC‒MS analysis of metabolomics extracted from CDNVs was conducted. H UHPLC‒MS/MS analysis of chemical reference standards of HSYA was performed. I UHPLC‒MS/MS analysis of HSYA extracted from CDNVs was conducted. J KEGG disease analysis of target genes of the top three miRNAs in CDNVs was performed. K KEGG pathway analysis of target genes of the top three miRNAs in CDNVs was conducted

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Cell Communication and Signaling

ISSN: 1478-811X