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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: The intracellular interplay between galectin-1 and FGF12 in the assembly of ribosome biogenesis complex

Fig. 5

Hypothetical model of interplay between galectin-1, FGF12, NOLC1, TCOF1. Galectin-1 directly interacts with FGF12 in the cytosol and nucleus. Direct binding between these proteins inhibits the secretion of FGF12 (A). The nuclear function of FGF12—galectin-1 complexes remains unknown (B), but galectin-1 promotes the interaction of FGF12 with NOLC1 (C) and TCOF1 (D) and downregulates the binding of NOLC1 to TCOF1 (E)

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Cell Communication and Signaling

ISSN: 1478-811X