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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Discovery of a novel small molecule as CD47/SIRPα and PD-1/PD-L1 dual inhibitor for cancer immunotherapy

Fig. 7

Synergistic inhibition of MC38 tumor growth by combining SMC18 with radiotherapy. A-C Experiment scheme A, tumor volume B, and body weight C in MC38 tumor-bearing mice. C57BL/6 mice were implanted with subcutaneous MC38 tumor cells on the right side. Tumors locally received one 20 Gy dose IR, and 2 mg/kg of SMC18 was daily i.p. administered for 14 days. Daily saline was set as a negative control. n = 5. The data are presented as means ± S.E.M. Statistical significance was determined using the unpaired Student's t-test (***P < 0.001)

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Cell Communication and Signaling

ISSN: 1478-811X