Fig. 6

Histopathological analysis of hematotoxicity in mice. A, B C57BL/6 mice were subjected to daily intraperitoneal injections of the SMC18 or an equivalent saline solution for 14 days. Blood samples were collected and assessed for red blood cell (RBC) count A (left), hemoglobin levels A (right), as well as the levels of glutamic pyruvic transaminase (ALT) and glutamic oxaloacetic transaminase (AST) in mice B. C The major organs including the heart, liver, spleen, lung, and kidney were dissected from the mice, and tissue sections were prepared and stained with H&E prior to scanning. Representative images of the organ tissues were captured. (Scale bar: 100 μm)