Fig. 3From: From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathyA schematic overview of LMNA mutant pathways and MAPK3/1 (ERK1/2) initiated changes in cardiac remodeling. Altered inter- and intracellular pathways lead to cellular phenotypic differences, giving rise to typical LMNA hallmarks, such as DNA damage, impaired actin cap and alterations in mechanoresponsesBack to article page