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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Multiregion WES of metastatic pancreatic neuroendocrine tumors revealed heterogeneity in genomic alterations, immune microenvironment and evolutionary patterns

Fig. 1

The flowchart of study design. Using Single-Nucleotide Variant (SNV) profiles derived from WES data, we categorized patients into two groups: those with mutated MEN1/DAXX (MEN1/DAXXmut, n = 7) and those with wild-type MEN1/DAXX (MEN1/DAXXwild, n = 3). Subsequently, we conducted analyses to explore differences between these two groups in the following aspects: (1) heterogeneity in genomic alterations, (2) characteristics of the immune microenvironment, and (3) evolutionary patterns

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Cell Communication and Signaling

ISSN: 1478-811X