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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: The in vitro and in vivo depigmentation activity of coenzyme Q0, a major quinone derivative from Antrodia camphorata, through autophagy induction in human melanocytes and keratinocytes

Fig. 7

CoQ0 suppressed p-MITF and tyrosinase expression through autophagy in B16F10 cells. Cells were pretreated with or without 3-MA (1 mM, 1 h), followed by CoQ0 (0-5 μM) for 4 h (A, B) or 24 h (C, E). At the end of the treatment, the p-MITF (A, B), tyrosinase, and LC3B (C, E) levels were measured using immunofluorescence staining. The results are the mean ± SD (n=3). ***p < 0.001 compared with untreated cells. ###p < 0.001 compared with CoQ0-treated cells

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Cell Communication and Signaling

ISSN: 1478-811X