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Fig. 11 | Cell Communication and Signaling

Fig. 11

From: The in vitro and in vivo depigmentation activity of coenzyme Q0, a major quinone derivative from Antrodia camphorata, through autophagy induction in human melanocytes and keratinocytes

Fig. 11

CoQ0 induced autophagy flux in HaCaT cells. Cells were first treated with or without 3-MA (1 mM, 1 h) and/or CQ (1 μM, 1 h) followed by CoQ0 (0-5 μM, 24 h). A, B Cells were transfected with the GFP-LC3 expression vector, and the formation of GFP-LC3 puncta induced by CoQ0 was observed under a confocal microscope. C, D Intracellular AVO formation in cells was observed under a fluorescence microscope. The results are the mean ± SD (n=3). *p < 0.05; ***p < 0.001 compared with untreated cells. ###p < 0.001 compared with CoQ0-treated cells

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Cell Communication and Signaling

ISSN: 1478-811X