Fig. 8

Short-time effect of acidic media on MAPK in HK-2 and CCD1092Sk cells in coculture. Protein expression changes of phosphorylated and total ERK1/2, JNK1/2 and p38 in HK-2 (a-c, g-i, m–o) and CCD-1092Sk (d-f, j-l, p-r). Representative western blots of proteins isolated from cells exposed to acidosis (s-t). Comparison of acidosis-effect in HK-2 and CCD-1092Sk on ERK1/2 (6u), JNK1/2 (6v) and p38 (6w). n = 6—9. exposure time = 3 h