Fig. 5

Prospective research directions in molecular interrelation between mTOR signaling and polyploidy: (A) The established links between polyploidy and mTOR signaling individually with cancer, diabetes and aging are well documented. However, the molecular connection between polyploidy and mTOR signaling remains to be elucidated. B Schematic illustration of the envisaged future research endeavors aimed at uncovering the intricate molecular association between polyploidy and mTOR signaling