Skip to main content
Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Pan-histone deacetylase inhibitor vorinostat suppresses osteoclastic bone resorption through modulation of RANKL-evoked signaling and ameliorates ovariectomy-induced bone loss

Fig. 7

Administration of SAHA ameliorates ovariectomy-induced bone loss in mice. A Schematic diagram for the in vivo experiments. B Body weight variations of mice in each group during the period of surgery and intraperitoneal SAHA injection. C-D Quantitative statistics of the serum levels of bone resorption markers TRAcP-5b and β-CTx. Bar graphs are shown as mean ± SD, n = 6 per group. *p < 0.05, **p < 0.01, ***p < 0.001 and ns: no significance, relative to the sham-operated group and OVX-untreated group

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X