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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes

Fig. 2

Global DNA 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) levels are affected by ovarian stimulation (OS) in the parthenogenetic early embryos. A Representative developmental images of parthenogenetically activated embryos with each stage. B Analysis of ratios of 5mC/5hmC within each group (n = 28–60). Data are expressed as the means ± standard deviation (SD), ***P < 0.001. (unpaired two-tailed t test). Scale bar = 100 μm

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