Fig. 1
From: PRMT1 in human neoplasm: cancer biology and potential therapeutic target
The genomic and protein structure of PRMT1. A The genomic structure of the PRMT1 gene consists of 12 constitutive exons, with exon 1 further divided into 4 alternative exons. The PRMT1 gene generates PRMT1 isoforms (v1 to v7) through transcription and splicing, along with the exon composition of these isoforms. Intron boundaries sequences are represented by the black boxes. B The protein structure of PRMT1-v2, which is the signature motifs (I, Post-I (PI), II, III), double E motif, and THW loop (adapted from [6])