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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of HPV-related cervical neoplasms

Fig. 2

Biogenesis of circRNAs. Pre-mRNA transcripts can undergo (a) intron-pairing driven circularization, b RBP-mediated circularization, c lariat-driven circularization, d direct circularization of lariat introns, and/or e tRNA splicing-driven circularization to produce circRNAs. EIciRNAs, ecircRNAs, and ciRNAs are the major circRNAs generated by the mentioned circularization methods. The newly produced circRNAs principally serve as protein and miRNA sponges to regulate diverse molecular mechanisms and cellular processes. The figure has been created by https://www.BioRender.com

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Cell Communication and Signaling

ISSN: 1478-811X