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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of HPV-related cervical neoplasms

Fig. 1

Pathophysiology of cervical cancer. Although genetic mutations and epigenetic alterations can give rise to the onset of CC, HPV infection is also considered a major leading cause for the progression of this gynecological malignancy. Circ-ATP8A2 and circSLC26A4 are key circRNAs, being involved in CC pathogenesis by up-regulating HOXA1 and EGFR mRNAs through sponging specific miRNAs. The figure has been created by https://www.BioRender.com

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Cell Communication and Signaling

ISSN: 1478-811X