Fig. 2
From: Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli
Identification of direct Egr-1 target genes and bioinformatics analysis. A Genome-wide occupancy of Egr-1 was investigated by ChIP-seq. ChIP-seq density heatmaps in bacterium-infected and control hBMEC for Egr-1 at TSS ± 3,000 bp. B Venn diagram showing the correlation analysis of Egr-1 peaks in infected and control hBMEC. C Distribution of genomic features of all accessible regions. Ten annotations were examined: promoter ( < = 1 kb), promoter (1 − 2 kb), promoter (2 − 3 kb), 1st exon, other exon, 1st intron, other intron, distal intergenic, 3′ untranslated region, downstream ( < = 300)