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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: PRDX6-iPLA2 aggravates neuroinflammation after ischemic stroke via regulating astrocytes-induced M1 microglia

Fig. 6

Inhibition of astrocytic PRDX6-iPLA2 influences Drp1-dependent mitochondrial fission through mediating the generation of ROS. a Mitochondrial morphology. b Mitochondrial membrane potential. c Western blot analysis of Drp1, cyto-Drp1, p-Drp1, mitochondrial Drp1 in CTX-TNA2 cells. d Western blot analysis of fission-related proteins and fusion-related factors in CTX-TNA2 cells. e DCFH-DA staninig and quantification of ROS. Values are mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X