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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over β-arrestin recruitment and receptor internalization

Fig. 5

Chemokine bias index at CXCR2. Bias indexes for each chemokine between different pathways were calculated using Calculation 2 using CXCL8 as the reference chemokine. The data are represented as boxplots, which depicts the range from minimum to maximum, with a central line indicating the median across five independent experiments. Significant differences were marked with *(P < 0.05), **(P < 0.01), ***(P < 0.001) or ****(P < 0.0001), non-significant differences were marked as ns. The dashed line represents the mean value of CXCL8, being 0

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Cell Communication and Signaling

ISSN: 1478-811X