Fig. 3
From: Sirtuins in kidney diseases: potential mechanism and therapeutic targets
Molecular role of sirtuins in podocytes, endothelial cells, and mesangial cells. NF-κB, nuclear factor kappa B; SREBP1, sterol regulatory element-binding protein 1; H3K9, histones3 lysine9; Nrf2, nuclear factor-erythroid 2-related factor 2; eNOS, endothelial nitric oxide synthase; NLRP3, NOD-like Receptor Pyrin Domain Containing 3; SOD, superoxide dismutase; ROS, reactive oxygen species; HIF-1ɑ, hypoxia-inducible factor-1; FOXO, forkhead box O. (Created with BioRender.com)