Fig. 7

MSR ablation prevents systemic and pulmonary inflammation caused by ferritin. A and B Neutrophil frequency in peripheral blood and lung tissue of WT and MSR KO mice after ferritin treatment. C and D After ferritin treatment, lung tissue monocytes and Ly6C+ neutrophils frequency in WT and MSR KO mice. E Lung wet-to-dry ratio of WT and MSR KO mice with 12 h ferritin stimulation. F and G HE and morphological images of ferritin-injected WT and MSR KO mice. H, I, J and K After ferritin injection, serum levels of inflammatory factors including IL-6, MCP-1, TNF-α and IFN-γ in WT and MSR KO mice