Fig. 8From: Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitisProtective mechanism of ω-3 fatty acids against cytokine-induced apoptosis. The schematic model represents cytokine-mediated hydrolysis of phosphatidylcholine by PLA2G6, giving rise to ω-3 fatty acids, which protect β cells by reducing ADP-ribosylation through upregulating ARH3 expression via SUZ12Back to article page