Fig. 5
From: Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis
ARH3 regulates cytokine-mediated β-cell apoptosis. Western blot analysis of ARH3 siRNA (siARH3) MIN6 cells treated with cytokines (a) (BR: Biological replicates). b, c relative levels of ARH3 (b) and cleaved caspase 3 (c) bands normalized to LAMINB1. To ensure reproducibility, we performed 3 independent experiments. Statistical test: * p ≤ 0.05, ** p ≤ 0.01, and *** p ≤ 0.001 by 2wayANOVA and “Šídák’s multiple comparisons test