Fig. 4
From: Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis
Regulation of ADP-ribosylation enzymes by pro-inflammatory cytokines and Phospholipase enzyme. A-K Cytokine cocktail CT2 (IL-1β + IFN-γ + TNFα)-dependent protein expression of ADP-ribosylation enzymes and PARP-mediated apoptosis markers in Pla2g6 siRNA (siPla2g6) MIN6 cells (n = 5, +SD). Statistical test: * p ≤ 0.05, ** p ≤ 0.01, and *** p ≤ 0.001 by 2wayANOVA and “Šídák’s multiple comparisons test