Fig. 2From: Macrophage barrier in the tumor microenvironment and potential clinical applicationsStructure and functions of CAR-macrophages. A CAR consists of three domains: antigen recognition domain, transmembrane domain, and intracellular signaling domain. B CAR-Macrophages have the ability to recruit and activate T cells, NK cells, and DCs within tumors. They also exhibit enhanced phagocytic capabilities and possess an advantage in infiltrating solid tumors effectivelyBack to article page