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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: IL13Rα2 as a crucial receptor for Chi3l1 in osteoclast differentiation and bone resorption through the MAPK/AKT pathway

Fig. 7

rIL13Rα2 protein suppresses LPS-induced calvarial osteolysis. A mouse model was constructed and divided into saline, LPS, LPS+ 0.5 μg/ml rIL13Rα2, and LPS + 1 μg/ml-rIL13Rα2 groups. A Representative images of three-dimensional reconstructions of the calvarial bone were obtained using a micro-CT scanner. B Histograms of the bone volume fraction (BV/TV). C Histograms of the pore numbers. D Histograms of the percentage of bone porosity. E Representative images of HE and TRAP staining. F Histograms of the number of TRAP-positive osteoclasts. **P < 0.01. Results are presented as means ± SD

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Cell Communication and Signaling

ISSN: 1478-811X