Fig. 2From: Role of ferroptosis in chronic kidney diseaseMetabolism of iron in cells. Iron metabolism is important for life. Fe3+ is mainly combined with TF to form TBI and then enters cells through endocytosis, while Fe2+ enters cells through DMT1, ZIP, LTCC and other pathways. Iron in LIP can be stored in FT or used by mitochondria. Iron output occurs mainly through FPN1Back to article page