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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Role of ferroptosis in chronic kidney disease

Fig. 2

Metabolism of iron in cells. Iron metabolism is important for life. Fe3+ is mainly combined with TF to form TBI and then enters cells through endocytosis, while Fe2+ enters cells through DMT1, ZIP, LTCC and other pathways. Iron in LIP can be stored in FT or used by mitochondria. Iron output occurs mainly through FPN1

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