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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Extracellular succinate derived from ectopic milieu drives adhesion and implantation growth of ectopic endometrial stromal cells via the SUCNR1 signal in endometriosis

Fig. 1

Altered metabolic profiles of peritoneal fluid in EMs compared with Healthy. A A PLS-DA score plot of EMs and Non-EMs in cohort. R2X = 0.24, R2Y = 0.231, Q2 = 0.541. B, C Volcano plot and bar graph of the differential metabolites in EMs and Non-EMs filtered by univariate analysis. D Hierarchical clustering of the 22 differential organic acid metabolites (FC > 1.2, p < 0.05) in non-EMs and EMs group. Blue indicates a decreased level; red indicates an increased level. E Bubble plot for quantitative enrichment analysis showing the metabolic pathway changes between EMs and non-EMs metabolomes in cohort

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