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Table 1 Comparison between Eukaryotes, Prokaryotes, and Archaea EVs

From: Prokaryotic microvesicles Ortholog of eukaryotic extracellular vesicles in biomedical fields

Domains of life

Origin

Diameter (nm)

Terms

Eukaryotes

Mammalian cells

Apoptosis process: with origin cell membrane and components

1000–5000

Apoptotic bodies (ABs)

The outward budding of the cell membrane

100–1000

Microvesicles, Extracellular membrane vesicles, Microparticles, Ectosomes, Exovesicles

Endosomal origin: early and late endosome for intraluminal vesicles (ILVs) formation then Multivesicular Bodies (MVB) fusion with the cell membrane

30–150

Exosomes (Exos)

Prokaryotes

Gram-negative bacteria

Outer membrane

10–500

Outer membrane vesicles (OMVs)

Gram-positive bacteria

Cytoplasmic membrane

20–400

Membrane vesicles (MVs)

Archaea

Archaea

Cytoplasmic membrane

50–230

Membrane vesicles (MVs)